NES Games
Genesis 
N64
SNES
NES
Sega
Roger Clemens' MVP Baseball (1991)
Rollerball
Rollerblade Racer
Rollergames
Rolling Thunder
Romance of the Three Kingdoms (1986)
Roundball: 2 on 2 Challenge
Secret Scout
Section Z
Seicross
Sesame Street: 1-2-3- Sesame Street: A-B-C
Sesame Street: Big Bird's Hide & Speak
Sesame Street: Countdown
Shadow Warriors
Shadowgate (1989)
Shingen the Ruler
ShockWave (1990)
Shooting Range
Silent Assault
Silver Surfer
The Simpsons: Bart vs. the World
The Simpsons: Bartman Meets Radioactive Man
Skate or Die 2
Ski or Die
Skull and Crossbones
Sky Kid
Sky Shark
Slalom
Snoopy's Silly Sports Spectacular
Soccer Nintendo
Solar Jetman: Hunt for the Golden Warpship
Solitaire
Solomon's Key (1986)
Space Shuttle Project
Spelunker
Spot
Sqoon
Stack-Up
Stadium Events
Stanley: The Search for Dr. Livingston
Star Force
Star Trek 25th Anniversary
Star Voyager
Star Wars
StarTropics
Stealth ATF (Stealth Eagle)
Stinger
Street Cop
Stunt Kids